01 - Preheat the oven to 425°F. Line a baking sheet with parchment paper.
02 - Toss the radishes with olive oil, sea salt, and black pepper in a large bowl. Spread them cut side down on half of the prepared baking sheet.
03 - Roast the radishes for 10 minutes to begin the cooking process.
04 - Whisk together the honey, hot sauce, Dijon mustard, soy sauce, lemon juice, garlic powder, salt, and pepper in a small bowl until smooth.
05 - Pat the salmon fillets dry with paper towels. Lightly season both sides with salt and black pepper.
06 - Remove the baking sheet from the oven. Move the radishes to one side and place the salmon fillets skin-side down on the other side.
07 - Brush the tops of the salmon fillets generously with the hot honey glaze. Reserve a small amount of glaze for serving.
08 - Return the baking sheet to the oven and roast for 12–15 minutes, until the salmon flakes easily with a fork and the radishes are tender and caramelized.
09 - For extra caramelization and color, broil the salmon for an additional 1–2 minutes.
10 - Drizzle the remaining hot honey glaze over the salmon. Garnish with fresh parsley or chives and serve with lemon wedges.